ISSN: 2578-6571
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RESEARCH ARTICLE Pages 38-43
Abstract: Prediction models are widespread used as surrogate markers of disease severity, benchmarking and resource allocation in critical care. After derivation, they should pass through validation in different settings before their general use in other populations.
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SHORT COMMUNICATION Pages 35-37
Abstract: Cerebrospinal Fluid (CSF) analysis acquired a great role in the 1990's when applied to Multiple Sclerosis (MS) diagnostic work-up. The "watery fluid" by Andreas Vesalius remained unstudied till the introduction of Lumbar Puncture (LP) at the eighteenth century.
Research Article Pages 25-34
Abstract: To observe the effect of a Xixin decoction on learning and memory in APP/PS1 transgenic mice in addition to hippocampal ultrastructure and hippocampal Aβ42 related regulatory enzymes.
Review Article Pages 20-24
Abstract: Reduction of dopamine release from striatal dopaminergic neurons due to neuronal death is the main accepted concept of Parkinson's disease. Parkinson's disease begins years before a clinical diagnosis can be consistently made (asymptomatic/slightly symptomatic patients).
Review Article Pages 12-19
Abstract: Evidence is accumulating that inflammatory processes play a role in the pathophysiology of schizophrenia. This suggests that anti-inflammatory drugs might have beneficial effects in the treatment of schizophrenia patients. Statins have cholesterol independent effects on inflammation and oxidative stress and could potentially improve positive, negative and/or cognitive symptoms of schizophrenia.
Research Article Pages 4-11
Abstract: Data emerging that maternal consumption of moderate amount of caffeine will affect the development of the fetus and later the cognitive function of the brain. The aim of this study was to determine the effect of caffeine administration in pregnant mice on the learning and memory and motor coordination of offspring's at one and a half months of age.
Review Article Pages 1-3
Abstract: Our discovery of the involvement of the interaction between intracellular signalling pathways mediated by Ca2+ and cAMP (Ca2+/cAMP interaction) in the neurotransmission and neuroprotection has produced new avenues in the understanding of the cellular and molecular mechanisms involved in the pathogenesis of neurological and psychiatric disorders, such as Alzheimer's and Parkinson's diseases.
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